Yes! Yes! Yes! Because our juices are raw and not processed in any way, they are very perishable. We want to keep those enzymes and nutrients alive and well and breaking down in your body, not in the bottle! Our juices rapidly lose nutritional value and taste when left unrefrigerated. All of our juice and nut milks need to be kept at 40 degrees or below at all times. On the run? Put those babies on some ice in a cooler my friends. At home? They live in the fridge.